Sordaria macrospora is a species of microscopic fungus. It is one of several fungal model organisms in biology, e.g. the model of fruiting body development in Ascomycetes. It is a homothallic, self-fertile organism.
Uncinula macrospora is a plant pathogen that causes a powdery mildew disease of certain North American trees. Its hosts include various elms (Ulmus spp.), hackberries (Celtis spp.), and American hop hornbeam Ostrya virginiana .