Matthäus Merian (1621 – 1687), was a Swiss engraver and portrait painter.
He was born in Basel as the son of Matthäus Merian the Elder, and like his father became an engraver. He was the half-brother of Maria Sybilla Merian and the brother of Caspar Merian. He is documented as having served Carl Gustaf Wrangel as an importer of wine and other luxury goods and is known for his portraits. He became a teacher of Bartholomäus Kilian.
He died in Frankfurt am Main.