Mahamat Zene Cherif (born 1964) is a Chadian diplomat. Since 24 December 2017, he has been the Minister of Foreign Affairs for the Republic of Chad. He previously served as the Permanent Representative of Chad to the United Nations in New York.
Zene has a Master of Laws degree from the Taras Shevchenko National University of Kyiv. He joined the Chadian foreign ministry in 1993. From 2007 to 2013, he was the ambassador of Chad to Ethiopia and Chad's Permanent Representative to the African Union and the UN Economic Commission for Africa.
Zene has worked in a variety of other government posts and was Business Director of Air Chad in 1997 and 1998.