The Mollie Kathleen Gold Mine is a historic vertical shaft mine near Cripple Creek, Colorado. The mine shaft descends 1,000 feet (300 m) into the mountain, a depth roughly equal to the height of the Empire State Building in New York City. The mine currently gives tours, and is visited by around 40,000 people annually. The addition of the mines and subsequent tours of this mine and others in the area had considerable effect on the economies of both Victor, Colorado and Cripple Creek.

Mollie H. Beattie (April 27, 1947 Glen Cove, Long Island – June 27, 1996) was an American conservationist, and director of the United States Fish and Wildlife Service. In 2009, she was designated a Women's History Month Honoree by the National Women's History Project.

Mollie Wade Holmes Adams (October 8, 1881 – December 14, 1973) (Upper Mattaponi) was a tribal elder and advocate of tribal culture in Virginia. She advocated for recognition of the tribe and worked to preserve traditional skills and knowledge. She was selected for the Virginia Women in History program by the Library of Virginia.

Mollie Slott (April 19, 1893 – January 24, 1967) was an American journalist. She kept the Chicago Tribune-New York Daily News Syndicate running in its mid-century glory days.

Mollie Huston Lee (January 18, 1907 – January 26, 1982) was the first African American librarian in Raleigh, North Carolina and the founder of Raleigh's Richard B. Harrison Public Library, the first library in Raleigh to serve African Americans. Her greatest achievement was developing, maintaining, and increasing public library service to the African American people of Raleigh and Wake County, North Carolina while striving to achieve equal library service for the entire community.

Mollie Sneden (January 13, 1709 – January 31, 1810) born as Mary Dobbs was the operator of a ferry service at Palisades, New York in the United States, before and after the American Revolution. During the war she was prohibited from running the ferry because of her British sympathies. Mollie Sneden is listed as a Woman of Distinction by the New York Senate.

Mary E. Sawyer (1846-1902), better known as Mollie Monroe, was an American old west woman who was known for crossdressing and for her liaisons with multiple men, among other things.