Lionel Cranfield may refer to:

Lionel Lord Cranfield (11 October 1883 – 17 May 1968) played first-class cricket for Gloucestershire and Somerset between 1903 and 1922. He was born in Brixton, London and died at Sale, Cheshire.

Lionel Cranfield, 1st Earl of Middlesex (1575 – 6 August 1645) was an English merchant and politician. He sat in the House of Commons between 1614 and 1622 when he was raised to the peerage as Baron Cranfield.

Lionel Cranfield, 3rd Earl of Middlesex (1625 – 26 October 1674) was an English peer, styled Hon. Lionel Cranfield from 1640 until 1651.