E. B. Wilson may refer to:

Richard Biggerstaff "Dick" Wilson (February 25, 1904 – May 1, 1991) was an entrepreneur and politician in British Columbia, Canada. He served as mayor of Victoria from 1961 to 1965.

Clifford Brittin Wilson (December 2, 1879 – January 1, 1943) was an American politician who was the 56th Lieutenant Governor of Connecticut from 1915 to 1921 and a mayor of Bridgeport, Connecticut.

Benjamin Birdsall Wilson (11 December 1879 – 14 September 1957) was an English first-class cricketer, who played 185 games for Yorkshire County Cricket Club between 1906 and 1914.

Thomas Burrell Wilson (December 12, 1852 in Hall, Ontario County, New York – January 11, 1929 in Hall, Ontario Co., NY) was an American politician from New York.

Samuel B. Wilson (born Samuel Wilson) (March 17, 1783 – August 1, 1869) was a Virginia theologian and professor. He served a brief period as acting President of Hampden–Sydney College in 1847.