Deborah Jeane Palfrey (March 18, 1956 – May 1, 2008), dubbed the D.C. Madam by the news media, operated Pamela Martin and Associates, an escort agency in Washington, D.C. Although she maintained that the company's services were legal, she was convicted on April 15, 2008 of racketeering, using the mail for illegal purposes, and money laundering. Slightly over two weeks later, facing a prison sentence of five or six years, she was found hanged. Autopsy results and the final police investigative report concluded that her death was a suicide.

A palfrey is a type of horse that was highly valued as a riding horse in the Middle Ages. It was a lighter-weight horse, usually a smooth gaited one that could amble, suitable for riding over long distances. Palfreys were not a specific breed as horse breeds are understood today.

Simon Palfrey is an English Scholar at Oxford University and a Fellow in English at Brasenose College, Oxford University. He specialises in Shakespeare and Renaissance literature.

The term Palfrey may refer to:

Michelle Palfrey is an American soccer player from Monrovia, California who plays as a forward.