Daniel Murphy may refer to:

Daniel Joseph Murphy (September 10, 1864 – December 14, 1915) was a professional baseball catcher. He played part of one season in Major League Baseball for the New York Giants of the National League in 1892. In 8 games with the Giants, he had a .115 batting average.

Danny Murphy (born 8 February 1960) is a former Australian rules footballer who played with North Melbourne in the Victorian Football League (VFL).

Danny Murphy (22 February 1884 – 1 November 1956) was an Australian rules footballer who played with Fitzroy in the Victorian Football League (VFL).

Danny Murphy (born 2003/2004) is a British deaf actor who will appear in the upcoming film The Parts You Lose alongside Aaron Paul. Murphy is fluent in British Sign Language.